Detroit Lions at San Francisco 49ers: Week 2 Betting Pick

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The Detroit Lions (+3) are heading west to take on the San Francisco 49ers at Levi’s Stadium. This late afternoon game kicks off at 4:05 p.m. ET and fans can watch the action on FOX.

Betting Preview: Detroit Lions at San Francisco 49ers

In this Sunday NFC game, San Francisco is getting picked as the favorite and the team’s currently giving up 3 points. The Lions are also receiving +130 moneyline odds while the 49ers are -150. Some decent live betting opportunities may exist during the game.

Sharp bettors are siding with the Niners, as the line opened at 2.

The Lions have gone 0-1 straight up (SU) in 2018 while the 49ers are also 0-1 SU.

The Lions are still looking for their first win after a 48-17 loss to the Jets in Week 1. The passing game could’ve been sharper as the Lions completed 29-of-52 passes for 300 yards, one touchdown and five interceptions. Matthew Stafford went 27-for-46 for 286 yards, one touchdown and four interceptions while Matt Cassel completed two-of-six for 14 yards and one interception. Kerryon Johnson (only 17 rushing yards on five attempts) led the running attack while Kenny Golladay (seven receptions, 114 yards) and Golden Tate (seven catches, 79 yards, one TD) handled the receiving duties in the defeat.

San Francisco just fell 24-16 to Minnesota a week ago. The defense allowed the Vikings to run for 116 yards on 32 rush attempts. Adam Thielen had a good showing, recording 102 yards on six catches for Minnesota. For San Francisco, Jimmy Garoppolo completed 15-of-33 passes for 261 yards, one touchdown and three interceptions. Alfred Morris (38 yards on 12 rush attempts) and Matt Breida (46 yards on 11 carries) handled the running game as George Kittle (five receptions, 90 yards) and Trent Taylor (four catches, 28 yards) led the pass-catching corps in the loss..

Detroit Lions vs. San Francisco 49ers Betting Prediction

SU Winner: 49ers, ATS Winner: 49ers

Team Betting Trends

  • San Francisco has lost one fumble this season while Detroit has not lost any.
  • The Lions created 10 rushing touchdowns last season.
  • The 49ers put up 15 rushing touchdowns last season.
  • The Lions converted 29 passing touchdowns last season.
  • The 49ers put up 15 passing touchdowns last season.
  • The San Francisco defensive unit has notched three sacks on the year while Detroit has two.